POS-502 HISTOLOGICAL FEATURES OF LUPUS NEPHRITIS
نویسندگان
چکیده
منابع مشابه
Plasma CD147 reflects histological features in patients with lupus nephritis.
OBJECTIVE A glycosylated transmembrane protein, CD147, has been implicated in regulating lymphocyte responsiveness and leukocyte recruitment. As lupus nephritis (LN) often follows a relapsing-remitting disease course, accurate understanding of the disease activity would be extremely helpful in improving prognosis. Unfortunately, neither clinical nor serological data can accurately reflect the h...
متن کاملHistological and clinical evolution of lupus nephritis.
In recent years, lupus nephritis has become the major complication and the most pressing problem in patients suffering from lupus erythematosus disseminatus. The clinical course of the disease was different 15 years ago, when Keith (1940) wrote that "renal insufficiency does not play an important role in causing death". At that time patients usually died of a "lupus crisis" or as a result of co...
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It is known that anti-TNFα therapy has opened a new era in treatment of rheumatoid arthritis, and it is emerging as a new successful treatment in the current rheumatologic practice. Besides, there is evidence that this therapy is an important cause of iatrogenic autoimmune disease. Several studies reported the possible onset of lupus syndrome that can be resolved with withdrawal of anti-TNFα dr...
متن کاملThe prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
متن کاملRelation of peritubular capillary features to class of lupus nephritis
BACKGROUND Experimental studies have linked peritubular capillary (PTC) loss with progression of chronic kidney disease. Minimal information on PTC in lupus nephritis (LN) has been reported. We therefore evaluated the PTC area in different classes of LN and determined if specific clinical characteristics correlated with PTC changes. METHODS Renal biopsies of 253 subjects with LN (categorized ...
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ژورنال
عنوان ژورنال: Kidney International Reports
سال: 2021
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2021.03.529